2010

In-universe

 * Unknown date
 * Leelu is released into the wild and Fry searches for her with Mr. Panucci's cousin Leroy.

Real-world

 * 24 June
 * Episodes eighty-nine, "Rebirth", and ninety, "In-A-Gadda-Da-Leela", are aired on Comedy Central.
 * 1 July
 * Episode ninety-one, "Attack of the Killer App", is aired on Comedy Central.
 * 8 July
 * Episode ninety-two, "Proposition Infinity", is aired on Comedy Central.
 * 15 July
 * Episode ninety-three, "The Duh-Vinci Code", is aired on Comedy Central.
 * 22 July
 * Episode ninety-four, "Lethal Inspection", is aired on Comedy Central.
 * 29 July
 * Episode ninety-five, "The Late Philip J. Fry", is aired on Comedy Central.
 * 5 August
 * Episode ninety-six, "That Darn Katz!", is aired on Comedy Central.
 * 12 August
 * Episode ninety-seven, "A Clockwork Origin", is aired on Comedy Central.
 * 19 August
 * Episode ninety-eight, "The Prisoner of Benda", is aired on Comedy Central.
 * 26 August
 * Episode ninety-nine, "Lrrreconcilable Ndndifferences", is aired on Comedy Central.
 * 2 September
 * Episode one-hundred, "The Mutants Are Revolting", is aired on Comedy Central.
 * 21 November
 * Episode one-hundred and one, "The Futurama Holiday Spectacular", is aired on Comedy Central.
 * 21 December
 * Volume 5 is released.