Anti-pressure pill

The anti-pressure pill as developed by Professor Farnsworth allows the user to survive in a high-pressure environment such like the ocean floor in up to three miles depth. There are no apparent side effects. However, the pill is not very user friendly, as it is about the size of a goose egg and is taken as a suppository.

Trivia

 * This is the origin of the minor internet meme "Good news! It's a suppository".