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In-universe

 * Unknown date
 * Earth is covered in water, and a bloodthirsty shrimp attacks Fry, Bender and the Professor.
 * The situation of geography of the world beyond what Fry, the Professor, and Bender (and the viewer) saw remains unknown
 * The situation of life on Earth (particularly human life) remains unknown, save for a giant bloodthirsty shrimp (and possibly merfolk, if said shrimp used one as a lure).