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|First appearance||"The Duh-Vinci Code" (6ACV05)|
|Voiced by||David Herman|
Biff is a bully on Planet Vinci, who constantly mocks Leonardo da Vinci and eventually leads him to lead an attack on the planet with his doomsday device. [6ACV05]
- His appearance, voice and character are a reference to Biff Tannen, from the Back to the Future trilogy.
- When teasing Leonardo he mentions the Higgs boson.
Biff: Some doomsday machine! It barely killed anyone!