|Location||Earth, Pacific Ocean|
|First appearance||"In-A-Gadda-Da-Leela" (6ACV02)|
The Lo'ihi Island is located on the Pacific Ocean. Zapp and Leela crash landed there after first attacking the V-GINY, believing it to be another planet. Due to its mild climate and food as well as delusions, Leela come to believe it is a divine metaphor for a second Garden of Eden, and decides to repopulate the human race with Zapp after thinking Earth has been destroyed.
This island is inhabited by a species of talking snakes. Thought it's possible the talking part is an illusion. The snake Leela spoke to could have not been able to speak at all, because as she was delirious from dehydration she could have imagined it.
There's plenty of trees on the Lo'ihi Island. It even has apple trees.
- Apparently, Lo'ihi is an independent country. (7ACV03)
- Probably based on the Lōʻihi Seamount, an active undersea volcano located around the island of Hawaii. In the year 3010, it has become an island.