|First appearance||Worlds of Tomorrow|
The female hypnotoad, which comes from a perpendicular universe, is the female equivalent of the Hypnotoad. Like her male counterpart, she a large toad with oscillating, multicolored eyes, who can hypnotize anything at will, including an entire crowd of Humans, by making a loud, buzzing noise. She has a pink bow on her head and a pink collar around her neck.
In 3017, the Hypnotoad hypnotized Professor Hubert J. Farnsworth, making him order the Planet Express crew to take him to Amphibios 9. Once there, the Hypnotoad commenced his buzzing noise, making hypnowaves that revealed the female hypnotoad from a perpendicular universe.
The universe was pulled into the hypnowaves, but Lord Nibbler saved Philip J. Fry from being sucked in as well. Fry worked with Nibbler, then later Professor Farnsworth, to restore New New York and the rest of Earth, as well as the other planets in the universe.